Volumes & Issues

Ferris LE, Fletcher RH

pp. 113-115 · DOI: 10.4103/0975-1483.63143 · 2010

Conflict of interest in medical publishing exists when a participant’s private interests compete with his or her responsibilities to the scientific community, readers and society. While conflict of interest is common, it…

Shastri DH, Patel LD, Parikh RK

pp. 116-120 · DOI: 10.4103/0975-1483.63144 · 2010

The present work describes the formulation development of ophthalmic in situ gelling system using thermoreversible gelling polymer, i.e. Pluronic F 127 (PF127). Because of high concentration (20 to 25%w/v) of this polyme…

Patil SA, Kuchekar BS, Chabukswar AR, Jagdale SC

pp. 121-129 · DOI: 10.4103/0975-1483.63147 · 2010

The purpose of this research was to formulate and characterize solid dispersion (SD) of metformin hydrochloride using methocel K100M as the carrier by the solvent evaporation and cogrinding method. The influence of drug …

Patel MA, Patel PK, Patel MB

pp. 130-136 · DOI: 10.4103/0975-1483.63149 · 2010

The present study was designed to evaluate the effects of aqueous extract of Ficus bengalensis Linn. bark (AEFB) on inflammatory bowel disease (IBD). Effects of AEFB were studied on 2, 4, 6-trinitrobenzenesulfonic acid (…

Mulla WA, Kuchekar SB, Thorat VS, Chopade AR, Kuchekar BS

pp. 137-14 · DOI: 10.4103/0975-1483.63152 · 2010

Extracts obtained from the leaves of various Alocasia species have been used in India as folk remedy for the treatment of various inflammatory ailments including rheumatism and bruise. The ethanolic extract of leaves of …

Aswar MK, Aswar UM, Subhedar NK

pp. 144-147 · DOI: 10.4103/0975-1483.63154 · 2010

In the present study, pancreas of rats were dissected and transferred to HEPES buffer (25 mM, pH 7.4). The control tissue pieces were kept in culture medium for one hour and the treated tissues were kept in same medium f…

Patel MA, Shah GB

pp. 148-151 · DOI: 10.4103/0975-1483.63156 · 2010

H2S has been proposed as physiological important molecule. It is considered as first endogenous gaseous K+ channel opener. K+ATP channel activity is mainly responsible for insulin secretion. K+ATP channel opening of β ce…

Sultanpur CM, Satyanarayana S, Reddy NS, Kumar KE, Kumar S

pp. 152-155 · DOI: 10.4103/0975-1483.63157 · 2010

Diabetes mellitus is a condition of increased blood glucose level in the body. Antihyperlipidemic drugs like statins and fibrates are widely used for prophylactic treatment in dyslipideamia and atherosclerosis. Diabetic …

Kurian GA, Seetharaman AV, Seetharaman NR, Paddikkala J

pp. 156-161 · DOI: 10.4103/0975-1483.63158 · 2010

Many challenges are associated with the oral delivery of insulin, relating to the physical and chemical stability of the hormone, and its absorption and metabolism in the human body. The present study aims to demonstrate…

R Nirmal, CR Prakash, K Meenakshi, P Shanmugapandiyan

pp. 162-168 · DOI: 10.4103/0975-1483.63162 · 2010

In our study, a series of novel 3-(4-(benzylideneamino) phenylimino) 4-fluoroindolin-2-one derivatives were synthesized and characterized by spectral (I.R, 1H NMR, mass) and elemental analysis. The title compounds (N1-N1…

Mondal P, Banerjee M, Jana S, Bose A

pp. 169-172 · DOI: 10.4103/0975-1483.63164 · 2010

Schiff bases of isatin with aminothiazole, its N-mannich bases and Spiro isatin derivatives were synthesized. Their chemical structures were confirmed by Infrared, 1H-Nuclear Magnetic Resonance data and elemental analysi…

Patel NB, Patel JC, Barat GG

pp. 173-182 · DOI: 10.4103/0975-1483.63165 · 2010

A series of 2-[2-(2,6-dichlorophenyl)amino]benzyl-3-(5-substituted phenyl-4,5-dihydro-1H-pyrazol-3-yl-amino)- 6,8-dibromoquinazolin-4(3H) ones 6a-m have been synthesized by the reaction of 2-[2-(2,6-dichlorophenyl) amino…

Rao KS, Jena N, Rao MEB

pp. 183-189 · DOI: 10.4103/0975-1483.63166 · 2010

A stability-indicating HPLC assay method has been developed and validated for valsartan in bulk drug and pharmaceutical dosage forms. An isocratic RP-HPLC was achieved on Waters 2695 using Symmetry C18 (250mm × 4.6mm × 5…

Giang Do T, Hoang Vu D

pp. 190-195 · DOI: 10.4103/0975-1483.63168 · 2010

Reversed-phase HPLC and UV spectrophotometric techniques using water as solvent have been developed and validated for the simultaneous determination of amoxicillin and cloxacillin in capsules. For both techniques, the li…

Galani VJ, Vyas M

pp. 196-200 · DOI: 10.4103/0975-1483.63169 · 2010

Aim of this investigation was to study the in vivo and in vitro drug interaction of glimepride with atorvastatin and rosuvastatin. In vitro drug interaction of glimepride with atorvastatin and rosuvastatin was studied us…

Devnani M, Gupta AK, Nigah R

pp. 201-205 · DOI: 10.4103/0975-1483.63170 · 2010

The ABC and VED (vital, essential, desirable) analysis of the pharmacy store of Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India, was conducted to identify the categories of items nee…

Kushwaha KSS, Kushwaha N, Rai AK

pp. 206-212 · DOI: 10.4103/0975-1483.63173 · 2010

Harmonization of pharmacy education has to be made a global agenda that will encompass the developments that have taken place in basic, medical, pharmaceutical sciences in serving the needs and expectations of the societ…