Journal of Young Pharmacists · Archive
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In this issue
Pharmaceutics
- Article
Sengel CT, Hascicek C, Gonul N
pp. 171-175 · DOI: 10.4103/0975-1483.83754 · 2011
The aim of this research was to investigate the effect of the duration of ultrasonication energy on the physicochemical characteristics of the nano-sized particulate drug delivery systems. For this purpose, meloxicam-loa…
- Article
Patel DM, Patel BK, Patel HA, Patel CN
pp. 176-180 · DOI: 10.4103/0975-1483.83755 · 2011
The objective of the present study was to evaluate the effect of sintering condition on matrix formation and subsequent drug release from polymer matrix tablet for controlled release. The present study highlights the use…
- Article
Yellanki SK, Jagtap S, Masareddy R
pp. 181-188 · DOI: 10.4103/0975-1483.83756 · 2011
An attempt to develop and evaluate mouth-dissolving film of phenobarbital for quick effect in treatment of epilepsy occurring in pediatric population has been made in the present study. Suitable film formers and plastici…
- Article
Gowda DV, Gowrav MP, Gangadharappa HV, Khan MS
pp. 189-196 · DOI: 10.4103/0975-1483.83757 · 2011
To minimize the unwanted toxic effects of anti-anginal ranolazine by kinetic control of drug release, it was entrapped into gastro-resistant, biodegradable eudragit (EU) and ethyl cellulose (EC) binary blend using phase …
- Article
Jagdale SC, Patil SA, Kuchekar BS, Chabukswar AR
pp. 197-204 · DOI: 10.4103/0975-1483.83758 · 2011
Metformin hydrochloride (MET) sustained-release solid dispersions (SD) were prepared by the solvent evaporation and closed melt method, using compritol 888 ATO as the polymer with five different drug–carrier ratios. Char…
- Article
Ghosh A, Biswas S, Ghosh T
pp. 205-210 · DOI: 10.4103/0975-1483.83759 · 2011
Silymarin is a hepatoprotective agent, having poor water solubility and oral absorption of about 23–47%, leading to low bioavailability of the drug. The aim of the present study is to improve the solubility and dissoluti…
- Article
Rajpurohit H, Sharma P, Sharma S, Purohit S, Bhandari A
pp. 211-215 · DOI: 10.4103/0975-1483.83763 · 2011
In the present study, fast disintegrating tablets were designed with a view to enhance patient compliance. In this method, the hull of Hordeum vulgare, cross carmellose sodium, and sodium starch glycolate were used as su…
- Article
Ekambaram P, Abdul Hasan Sathali A
pp. 216-220 · DOI: 10.4103/0975-1483.83765 · 2011
Solid lipid nanoparticles are typically spherical with an average diameter between 1 and 1000 nm. It is an alternative carrier system to tradition colloidal carriers, such as, emulsions, liposomes, and polymeric micro an…
Pharmacognosy
- Article
Jhade D, Ahirwar D, Jain R, Sharma NK, Gupta S
pp. 221-225 · DOI: 10.4103/0975-1483.83770 · 2011
Amaranthus spinosus Linn. (Amaranthaceae) is found throughout India. This tree species has been of interest to researchers because it is a medicinal plant employed in the Indian traditional system of medicine. Pharmacogn…
- Article
Bhandari M, Bhandari Anil, Bhandari A
pp. 226-231 · DOI: 10.4103/0975-1483.83771 · 2011
Natural compounds still play an increasingly important role in many areas of research and development. Their structural diversity is enhanced by the synthetic potential of combinatorial chemistry. Fractionation and separ…
Pharmacology
- Article
Silva FO, Silva MGV, Cerqueira GS, Sabino EB, Almeida AAC, Costa JP, Freitas RM
pp. 232-236 · DOI: 10.4103/0975-1483.83772 · 2011
The central nervous system (CNS) and anticonvulsant activities of iso-6-spectaline (SPEC) from Senna spectabilis were investigated in animal models. The SPEC from Senna spectabilis var. excelsa (Schrad) (0.1, 0.5 and 1.0…
- Article
Ahmed TS, Magaji MG, Yaro AH, Musa AM, Adamu AK
pp. 237-242 · DOI: 10.4103/0975-1483.83774 · 2011
Cochlospermum tinctorium A. Rich. (Cochlospermaceae) is a commonly used medicinal plant in the West Africa sub-region for the management of various conditions including pain and inflammatory conditions. In the present st…
Pharmaceutical Chemistry
- Article
Chaluvaraju KC, Bhat KI
pp. 243-245 · DOI: 10.4103/0975-1483.83775 · 2011
Studies were conducted on the anthelmintic property of about 15(e-h, 1e-1h, 2d-2f and 3e-3h) synthesized aminobenzylated Mannich bases bearing N-methyl piperazine using Indian earthworms Pheritima posthuma against pipera…
- Article
Satpathy R, Ghosh S
pp. 246-249 · DOI: 10.4103/0975-1483.83776 · 2011
Elvitegravir is a new-generation drug which acts as an integrase inhibitor of the HIV virus. The potential inhibition has been tested from the clinical trial data. Here the work basically deals with the quantitative stru…
Pharmacy Practice
- Article
Khan TM, Hassali MA, Al-Haddad MSM
pp. 250-255 · DOI: 10.4103/0975-1483.83778 · 2011
This study aims to identify the patient-physician communication barriers in the primary healthcare setting in Pulau Penang, Malaysia. A cross-sectional study was designed to attain the objectives of the study. A self-dev…
General Pharmacy
- Article
Wal P, Wal A, Gupta S, Sharma G, Rai AK
pp. 256-258 · DOI: 10.4103/0975-1483.83780 · 2011
Herbal formulations being widely accepted therapeutic agents as antidiabetics, antiarthritics, hepatoprotectives, cough remedies, memory enhancers, and adaptogens. The commonest myth regarding herbal medicines is that th…