Table of Contents

Mueen Ahmed KK

pp. 1-2 · DOI: 10.4103/0975-1483.51866 · 2009

I am pleased to introduce the Þ rst issue of “Journal of Young Pharmacists (An Addendum to InPharm Communique)”, an quarterly peer-reviewed publication of InPharm Association. As you all are aware, InPharm Communique was…

Jha D, Jasubhai K, Tomar MS

pp. 3-5 · DOI: 10.4103/0975-1483.51867 · 2009

Almost every pharmaceutical graduate, during the tenure of his/her study, is in a dilemma when it comes to choosing the professional Þ eld. Conventional jobs related to formulation, synthetic chemistry, analytical resear…

Saigal N, Baboota S, Ahuja A, Ali J

pp. 6-12 · DOI: 10.4103/0975-1483.51868 · 2009

Microcrystalline cellulose (MCC) has emerged as the most resourceful excipient of all times in drug research. Thanks to its profusion in terms of grades available for different needs and its physical properties that supp…

Jose S, Dhanya K, Cinu TA, Litty J, Chacko AJ

pp. 13-19 · DOI: 10.4103/0975-1483.51869 · 2009

Oral colon-targeted drug delivery systems have recently gained importance for delivering a variety of therapeutic agents for both local and systemic administration- local treatment of a variety of colonic diseases as wel…

Jain AK, Jain CP

pp. 20-23 · DOI: 10.4103/0975-1483.51870 · 2009

The present study involves the preparation and evaluation of buoyant microspheres using famotidine as a model drug for prolongation of gastric retention time. The microspheres were prepared by the solvent evaporation met…

Jeevana JB, Sunitha G

pp. 24-27 · DOI: 10.4103/0975-1483.51871 · 2009

To develop formulations for effective management of chronic pain without side effects associated with NSAIDs and COX-2 antagonists, Tramadol hydrochloride, an opioid antagonist, was encapsulated within Gelatin microspher…

Kumar AHS, Hynes BG, Mueen Ahmed KK

pp. 28-35 · DOI: 10.4103/0975-1483.51872 · 2009

The cellular network in vasculature is predominantly composed of two distinct cell types i.e., endothelial and smooth muscle cells, which along with the connective tissue and extracellular matrix govern the tone and func…

Golwala DK, Patel LD

pp. 36-41 · DOI: 10.4103/0975-1483.51873 · 2009

The present study deals with the macroscopical and microscopical studies of Bauhinia variegata Linn root. Some distinct and different characters were observed with sections of young, thick and very old and thick roots. T…

Reena R Nelson Anthikat, Michael A

pp. 42-45 · DOI: 10.4103/0975-1483.51874 · 2009

This study evaluates the antibacterial, antifungal, and antiviral properties of the areca nut in vitro using isolated organisms. A variety of human and veterinary isolates, both gram positive and gram negative, were test…

Kumar N, Mueen Ahmed KK, Dang R, Shivananda TN, Das K

pp. 46-48 · DOI: 10.4103/0975-1483.51876 · 2009

More than 300 constituents have been identiÞ ed in different propolis samples. This study investigated the composition of ethanolic extracts of propolis samples collected from the Gujarat zone. A gas chromatographymass s…

Patil VV, Pimprikar RB, Patil VR

pp. 49-53 · DOI: 10.4103/0975-1483.51879 · 2009

Pharmacognostical parameters for the leaves of Ficus bengalensis were studied with the aim of drawing the pharmacopoeial standards for this species: macroscopical and microscopical characters, physio-chemical constants, …

Gerlânia de Oliveira Leite, Antonia Rosângela Soares Penha, Glauberto Quirino da Silva, Aracélio Viana Colares, Fabíola Fernandes Galvão Rodrigues, José Galberto Martins Costa, André Luiz Herzog Cardoso, Adriana Rolim Campos

pp. 54-56 · DOI: 10.4103/0975-1483.51881 · 2009

Gastric ulcer is a serious gastrointestinal disorder that requires a well targeted therapeutic strategy. A number of drugs are available for the treatment of gastric ulcer, but clinical evaluation has shown incidence of …

Vaghasiya J, Rathod S, Bhalodia Y, Manek R, Malaviya S, Jivani N

pp. 57-62 · DOI: 10.4103/0975-1483.51883 · 2009

Objective: This study was designed to assess the effect of polyherbal formulation (PHF) on simvastatin hepatotoxicity in rats and to assess the possibility of co-administration of PHF along with hepatotoxic drugs. Method…

Yeshwante SB, Juvekar AR, Nagmoti DM, Wankhede SS, Shah AS, Pimprikar RB, Saindane DS

pp. 63-66 · DOI: 10.4103/0975-1483.51885 · 2009

The Anti-inflammatory activities of the methanol extract of Dillenia indica Linnaeus (Family Dilleniaceae) leaves were evaluated in various experimental models of inflammation to provide evidence for its traditional use.…

Gaur K, Kori ML, Tyagi LK, Singh V, Nema RK, Tripathi P, Sharma CS

pp. 67-71 · DOI: 10.4103/0975-1483.51884 · 2009

Licofelone (2-[6-(4-chlorophenyl)-2, 2-dimethyl-7-phenyl-2, 3-dihydro-1H-pyrrolizin-5-yl] acetic acid) is the Þ rst member of a new class of analgesic and anti-inß ammatory drugs acting by dual mechanism inhibiting both …

Ilango K, Valentina P, Umarani N, Kumar T

pp. 72-76 · DOI: 10.4103/0975-1483.51882 · 2009

The aim of this study was to design, synthesize, and investigate the in vivo anti-inß ammatory activity of some novel 2, 5-disubstituted - 1, 3, 4-oxadiazole derivatives. Ethyl-4-acetamido phenoxy acetate (I) was prepare…

Valentina P, Ilango K, Yamuna K, Purushothaman D, Samyuktha Rani A

pp. 77-81 · DOI: 10.4103/0975-1483.51880 · 2009

A quantitative structure activity relationship (QSAR) study on β-Carboline derivatives as an anti-tumor agent was performed with 30 compounds of β-Carboline derivatives on different cancer cell lines from reported work. …

Chakraborthy GS

pp. 82-85 · DOI: 10.4103/0975-1483.51878 · 2009

Medicinal plants provide good remedies for human diseases and play a vital role in our day-to-day lifes. Phyllanthus emblica Linn family- Euphorbiaceae, commonly known as amla, is an important household fruit. The anti-a…

Sonal Sekhar M, Aneesh TP, Sathianarayanan S, JinyVarghese K, Vasudevan DT, Revikumar KG

pp. 86-89 · DOI: 10.4103/0975-1483.51877 · 2009

A migraine is the most common cause of severe, recurring headache. With the recent advances in our understanding of migraine, it can be effectively treated and even prevented. Prophylactic treatment of migraines is indic…

Vinod KR, Sandhya S

pp. 90-93 · DOI: 10.4103/0975-1483.51875 · 2009

Pharma counseling is an important tool for any community pharmacist. With a 110 crore population, there is a tremendous opportunity for Pharma counselling on the Indian subcontinent. This could highlight a new beginning …