Article · Volume 1, Issue 1 · pp. 63-66
Anti-inflammatory activity of methanolic extracts of Dillenia indica L. leaves
Yeshwante SB1, Juvekar AR1, Nagmoti DM1, Wankhede SS1, Shah AS1, Pimprikar RB1, Saindane DS1
- 1University Institute of Chemical Technology, Matunga, Mumbai, INDIA.
Abstract
The Anti-inflammatory activities of the methanol extract of Dillenia indica Linnaeus (Family Dilleniaceae) leaves were evaluated in various experimental models of inflammation to provide evidence for its traditional use. Anti-inflammatory activity was observed in carrageenan-induced edema and acetic acid-induced capillary permeability. The methanol extract showed significant (P<0.01) anti-inflammatory activity in the paw edema test and acetic acid-induced capillary permeability at 200 mg/kg and 400 mg/kg. The extract at 100 mg/kg showed significant (P<0.05) activity in acid-induced permeability. These findings support the folkloric use of Dillenia indica for diseases related to inflammatory conditions.
Keywords: Anti-inflammatory; Dillenia indica; Dilleniaceae; leaves; methanolic extract
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