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Laurence Moon Bardet Biedl Syndrome with Maturity Onset Diabetes of the Young (Mody) - Case Report

1★, 1, 2★ Corresponding author

  1. 1Departemt of Pharmacy Practice, C.L. Baid Metha College of Pharmacy, Chennai, Tamil Nadu, INDIA.
  2. 2Department of Diabetology, Voluntary Health Services Hospital, Adyar, Chennai, Tamil Nadu, INDIA.

CORRESPONDENCE

Krishna Kumar Dhakchinamoorthi

Departemt of Pharmacy Practice, C.L. Baid Metha College of Pharmacy, Chennai, Tamil Nadu, INDIA.

krishnakumarrx@gmail.com

Received: 05-11-2018; Revised: 05-12-2018; Accepted: 24-12-2018.

Volume 11, Issue 1 · pp. 114-116 · 2019 · DOI: 10.5530/jyp.2019.11.25

ABSTRACT

Laurence-Moon-Bardet-Biedl syndrome (LMBBS) is an inherited genetic condition combination of two distinct disorders: Biedl-Bardet syndrome (BBS) and Laurence-Moon syndrome (LMS). BBS is characterized by polydactyly fingers or toes, obesity, renal failures and learning difficulties. The clinical signs of this condition vary among affected person, most person with Bardet-Biedl syndrome also develop a blurred central vision. LMS is a rare condition that may include cerebellar ataxia; vision abnormalities due to peripheral neuropathy; spastic paraplegia and intellectual disability. The cardinal clinical features include retinitis pigmentosa, obesity, polydactyly and hypogenitalism. The clinical complications significantly vary among differently affected siblings, include obesity, type 2 diabetes, elevated blood pressure and elevated cholesterol levels (hypercholesterolemia), renal complications, hypopituitarism; and short stature. This case study is first to report maturity-onset diabetes of the young (MODY) in LaurenceMoon-Bardet-Biedl syndrome among two south Indian patients.

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    Dhakchinamoorthi, K. K., Palathingal, J. T., & Sreenivasan, S. (2019). Laurence Moon Bardet Biedl Syndrome with Maturity Onset Diabetes of the Young (Mody) - Case Report. Journal of Young Pharmacists, 11(1), 114-116. https://doi.org/10.5530/jyp.2019.11.25

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    © 2019 Author(s)

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