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Antimicrobial Efficacy of Commercially Available Toothpastes – An In vitro Study

1, 1, 1, 2★, 3, 1★ Corresponding author

  1. 1Department of Periodontics, Sree Siddhartha Dental College and Hospital, Tumkur, INDIA.
  2. 2Department of Public Health Dentistry, Sree Siddhartha Dental College and Hospital, Tumkur, INDIA.
  3. 3Department of Microbiology, Sri Siddhartha Medical College and Hospital, Tumkur, INDIA.

CORRESPONDENCE

Darshana Bennadi

Department of Public Health Dentistry, Sree Siddhartha Dental College and Hospital, Tumkur, INDIA.

darmadhu@yahoo.com

Volume 7, Issue 3 · pp. 187-193 · 2015 · DOI: 10.5530/jyp.2015.3.8

ABSTRACT

Background: The use of antimicrobial chemotherapeutic agent has been proposed as a means of reducing the levels of oral bacteria. Many chemotherapeutic agents claim to have antimicrobial properties. Hence this in vitro study had been undertaken.Methods:This in vitro study comprised of seven toothpastes which have been tested for their antimicrobial activity against three oral pathogens namely, Streptococcus mutans, Escherichia coli and Candida albicans by well agar diffusion assay at the dilution of 1:1, 1:2, 1:4, 1:8 and 1:16.Results: Study results showed that toothpaste ‘five’ with sodium fluoride and sylodent as main ingredients showed maximum zone of inhibition against Streptococcus mutans where as against Candida albicans, toothpaste ‘six’ with xylitol and sodium fluoride as main ingredients showed maximum zone of inhibition. And against E. coli, toothpaste ‘one’ with Triclosan and Zinc sulphate as main ingredients showed maximum zone of inhibition among all toothpastes. It was observed that tooth paste ‘six’ with sodium fluoride and Neem, Meswak as main ingredient showed minimum zone of inhibition against Streptococcus mutans at 1:1 dilution among seven toothpastes used in the present study.Conclusion: In the present study, it has been demonstrated that triclosan containing toothpastes formulations are more effective in control of oral micro flora.

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    Roopavathi, K. M., Gopal, S. V., Pushpalatha, G., Bennadi, D., Renushri, B. V., & Madhura, A. S. (2015). Antimicrobial Efficacy of Commercially Available Toothpastes – An In vitro Study. Journal of Young Pharmacists, 7(3), 187-193. https://doi.org/10.5530/jyp.2015.3.8

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    © 2015 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0