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Transverse Leukonychia (Mees Lines) in Pediatric T-cell Acute Lymphoblastic Leukemia a Rare Manifestation During Combination Chemotherapy’s Maintenance Phase: A Case Report

1★, 1, 1, 1, 1, 1★ Corresponding author

  1. 1Department of Pharmacy Practice, KLE College of Pharmacy, Belagavi, Karnataka, INDIA.

CORRESPONDENCE

Manjula Gudhoor

Department of Pharmacy Practice, KLE College of Pharmacy, Belagavi, Karnataka, INDIA.

Received: 24-02-2024; Revised: 30-03-2024; Accepted: 21-07-2024.

Volume 16, Issue 4 · pp. 852-855 · 2026 · DOI: 10.5530/jyp.2024.16.108

ABSTRACT

An array of clinical manifestations, majority of which are relevant to dose and fade away after drug discontinuation, may accompany drug-induced nail abnormalities, but rarely do they endure over a long time. However, only a few groups of medications are reliably implicated in nail symptoms. Chemotherapeutic drugs have well-known effects on organs that include hair, skin and the digestive tract, which present clinically as exfoliative contact dermatitis, receding hair loss respectively. As a “skin” appendage, Nails are not an exemption. Patients undergoing systemic chemotherapy may experience an assortment of nail anomalies with chemotherapeutic drugs being the most common contributors. These alterations might only affect just one or many nails and could lead to discomfort and pain Nails. Transverse Lines can be passed down genetically or triggered by a range of illnesses and drugs. We report a case of a cancer patient who experienced transverse leukonychia as a result of antineoplastic therapy.

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    Gudhoor, M., Kumaresh, S., Sampagar, A., Doddannavar, A., Wakkundmath, G., & Kini, P. (2026). Transverse Leukonychia (Mees Lines) in Pediatric T-cell Acute Lymphoblastic Leukemia a Rare Manifestation During Combination Chemotherapy’s Maintenance Phase: A Case Report. Journal of Young Pharmacists, 16(4), 852-855. https://doi.org/10.5530/jyp.2024.16.108

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    © 2026 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0