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Advancements in Precision Medicine for Imaging and Pharmacotherapy in Atherosclerosis: Recent Discoveries and Emerging Technologies

1★, 2, 3, 3, 4★ Corresponding author

  1. 1Department of Pharmacology, NGSM Institute of Pharmaceutical Sciences, NITTE (Deemed to be University), Paneer, Derlakatae, Mangalore, Karnataka, INDIA.
  2. 2Pharmaceutical Analysis, Westfort College of Pharmacy, Thrissur, Kerala, INDIA.
  3. 3Department of Pharmaceutics and Pharmacy Practice, Nehru College of Pharmacy, Pampadi, Thrissur, Kerala, INDIA.
  4. 4Department of Pharmacy Practice, College of Pharmacy, Kannur Medical College, Anjarakandy, Kannur, Kerala, INDIA.

CORRESPONDENCE

Jithin Mathew

Department of Pharmacology, NGSM Institute of Pharmaceutical Sciences, NITTE (Deemed to be University), Paneer, Derlakatae, Mangalore, Karnataka, INDIA.

jithinmathew051@gmail.com

Received: 15-05-2024; Revised: 26-07-2024; Accepted: 16-08-2024.

Volume 16, Issue 4 · pp. 660-666 · 2024 · DOI: 10.5530/jyp.2024.16.84

ABSTRACT

Atherosclerosis is a primary factor in many cardiovascular diseases. Current treatments lack effectiveness in reducing the risk and progression of the disease, highlighting the need for better preventive measures. Precision medicine in cardiology offers personalized and patient-centered approaches to disease prevention and treatment. Innovations like machine learning and AI-assisted therapies are being explored to combat atherosclerosis, drawing from network medicine principles. This personalized approach involves analyzing gene regulation, metabolic pathways and protein interactions through mRNA therapeutics and immunomodulation techniques. Precision medicine shows promise in cardiovascular pharmacology by enabling targeted drug delivery and minimizing side effects. The review discusses AI-assisted drug discovery tools for individualized therapy and future prospects in nucleic acid-based treatments like antisense oligonucleotide therapeutics, aptamer therapy, siRNA-mediated treatments and gene slicing in precision medicine.

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    Mathew, J., Ragesh, K., Kunhunni, D. G. P., Sreekumar, S., & Chandrababu, A. (2024). Advancements in Precision Medicine for Imaging and Pharmacotherapy in Atherosclerosis: Recent Discoveries and Emerging Technologies. Journal of Young Pharmacists, 16(4), 660-666. https://doi.org/10.5530/jyp.2024.16.84

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    © 2024 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0