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Exploring the Connection between Hypothyroidism and Polycystic Ovary Syndrome: A Comprehensive Review

1, 2, 2★★ Corresponding author

  1. 1Program of Biochemistry, Faculty of Science, Assam down town University, Assam, INDIA.
  2. 2Program of Biotechnology, Faculty of Science, Assam down town University, Assam, INDIA.

CORRESPONDENCE

Nayan Talukdar

Program of Biotechnology, Faculty of Science, Assam down town University, Assam, INDIA.

nayan.new16@gmail.com

Received: 06-01-2024; Revised: 10-02-2024; Accepted: 16-02-2024.

Volume 16, Issue 2 · pp. 187-194 · 2024 · DOI: 10.5530/jyp.2024.16.25

ABSTRACT

Hypothyroidism and Polycystic Ovary Syndrome (PCOS) constitute prevalent endocrine conditions that have serious effects on the health of women. Hormonal dysregulation, ovarian dysfunction, and polycystic ovarian morphology are hallmarks of PCOS, whereas insufficient thyroid hormone production causes hypothyroidism. This study explores the complex interactions between hypothyroidism and PCOS, highlighting the urgent need for a thorough understanding of their coexistence. It is crucial to understand that PCOS and hypothyroidism frequently co-occur since they both involve similar metabolic and hormonal dysregulations. The complex interrelationship between these illnesses is further highlighted by genetic predispositions and epigenetic changes. Clinical manifestations and reproductive issues in afflicted people are mostly influenced by hormonal imbalances, insulin resistance, and metabolic abnormalities. It is crucial to use a multidisciplinary approach to patient treatment, collaborating with endocrinologists, gynaecologists, primary care doctors, nutritionists, and mental health specialists. This comprehensive approach takes into account not only the hormonal and metabolic components of PCOS and hypothyroidism but also the psychological well-being of persons dealing with these conditions. The importance of understanding and treating the interaction between PCOS and hypothyroidism in clinical practice is emphasized in this study. Improved results and a higher quality of life for afflicted people can result from early diagnosis and suitable care techniques. Future research initiatives on genetic, epigenetic, and metabolic issues also show potential for improving therapeutic and diagnostic approaches, eventually improving patient care. This review provides a comprehensive understanding of the challenges linked to PCOS and hypothyroidism, emphasizing the importance of a comprehensive treatment plan for improved outcomes.

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    Barman, I., Sharma, T., & Talukdar, N. (2024). Exploring the Connection between Hypothyroidism and Polycystic Ovary Syndrome: A Comprehensive Review. Journal of Young Pharmacists, 16(2), 187-194. https://doi.org/10.5530/jyp.2024.16.25

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    © 2024 Author(s)

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