Journal of Young Pharmacists logo
Submit
Journal of Young PharmacistsACADEMIC PUBLISHING
Article

Quality Standard of Safoof razyanaj: A Unani Polyherbal Powder Formulation

1, 1★, 1, 1★ Corresponding author

  1. 1Department of Ilmul Saidla (Unani Pharmacy), National Institute of Unani Medicine (NIUM), Bangalore, Karnataka, INDIA.

CORRESPONDENCE

Hamiduddin H

Department of Ilmul Saidla (Unani Pharmacy), National Institute of Unani Medicine (NIUM), Bangalore, Karnataka, INDIA.

drhamid2003@rediffmail.com

Received: 14-06-2019; Revised: 21-08-2019; Accepted: 06-09-2019.

Volume 11, Issue 4 · pp. 361-365 · 2019 · DOI: 10.5530/jyp.2019.11.74

ABSTRACT

Objectives: Safoof razyanaj (SR) a Unani polyherbal powder formulation used in dyspepsia, distension of stomach and anorexia. Standardization data of SR. by using scientific analytical procedures was established.Methods: Cleaned and dried powder of plant drug was prepared as per the method described in Unani Pharmacopeia of India (UPI). SR formulation was evaluated using physicochemical tests: powder characterization, extractive value, alcohol and water-soluble matter, Ash value, LOD at 105°C, pH and HPTLC fingerprinting.Results: SR color was light brown, aromatic and sweetish in taste. Physicochemical parameters expressed as mean values of the three readings showed loss of weight on drying, total ash, acid insoluble ash and watersoluble ash as 4.62 ± 0.10, 4.95 ± 0.05, 1.83 ± 0.03 and 2.10 ± 0.03 respectively. The Bulk density, tapped density, angle of repose, Hauser’s ratio and compressibility index were 0.46 ± 0.01, 0.56 ± 0.00, 35.62 ± 0.45, 1.23 ± 0.00 and 19.24 ± 0.59 respectively, pH of 1% and 10% solution were 4.78 ± 0.03 and 5.08±0.02 respectively. Extractive values in petroleum ether, benzene and ethyl alcohol by successive extraction method were 11.24 ± 0.14, 2.08 ± 0.04 and 6.73 ± 0.10 respectively. Extractive values in petroleum ether, benzene, ethyl alcohol and water by non-successive extraction method were 11.24 ± 0.14, 15.44 ± 0.24, 32.20 ± 0.13 and 34.28 ± 0.18 respectively. Qualitative analysis showed presence of alkaloid, tannin, terpenoid, protein, carbohydrate, phenol, glycoside, flavonoid and saponin. HPTLC fingerprinting data of SR in methanolic extract and mobile phase toluene: ethyl acetate: formic acid (5:4:1) was set in.Conclusion: Standardization data of SR was obtained.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Ikram, M., H, H., Rather, G. J., & Zaigham, M. (2019). Quality Standard of Safoof razyanaj: A Unani Polyherbal Powder Formulation. Journal of Young Pharmacists, 11(4), 361-365. https://doi.org/10.5530/jyp.2019.11.74

    Copyright and licence

    © 2019 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0